HMN214

CAS No. 173529-46-9

HMN214 ( HMN214; HMN 214; HMN-214 )

Catalog No. M17370 CAS No. 173529-46-9

HMN-214(IVX214) is a potent PLK1 inhibitor with an average IC50 of 0.12 μM.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 43 In Stock
5MG 69 In Stock
10MG 113 In Stock
25MG 207 In Stock
50MG 332 In Stock
100MG 478 In Stock
500MG 1062 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    HMN214
  • Note
    Research use only, not for human use.
  • Brief Description
    HMN-214(IVX214) is a potent PLK1 inhibitor with an average IC50 of 0.12 μM.
  • Description
    HMN-214 is an oral prodrug of HMN-176, a stilbene derivative that interferes with the subcellular spatial location of polo-like kinase-1, a serine/threonine kinase that regulates critical mitotic events.
  • Synonyms
    HMN214; HMN 214; HMN-214
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    PLK1
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    173529-46-9
  • Formula Weight
    424.47
  • Molecular Formula
    C22H20N2O5S
  • Purity
    98%
  • Solubility
    DMSO : 25 mg/mL 58.90 mM;
  • SMILES
    CC(=O)N(c1ccccc1/C=C/c1cc[n+](cc1)[O-])S(=O)(=O)c1ccc(cc1)OC
  • Chemical Name
    (E)-4-(2-(N-((4-methoxyphenyl)sulfonyl)acetamido)styryl)pyridine 1-oxide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Garland LL, et al. Clin Y Res. 2006 Sep 1;12(17):5182-9.
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