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HM90822

CAS No. 1363145-46-3

HM90822( —— )

Catalog No. M36356 CAS No. 1363145-46-3

HM90822 is a novel synthetic apoptotic protein (IAP) antagonist that induces apoptosis in human pancreatic cancer cells through proteasome-dependent degradation of IAPs containing the BIR2/3 structural domain.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
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50MG 2742 Get Quote
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Biological Information

  • Product Name
    HM90822
  • Note
    Research use only, not for human use.
  • Brief Description
    HM90822 is a novel synthetic apoptotic protein (IAP) antagonist that induces apoptosis in human pancreatic cancer cells through proteasome-dependent degradation of IAPs containing the BIR2/3 structural domain.
  • Description
    HM90822 is a novel synthetic apoptotic protein (IAP) antagonist that induces apoptosis in human pancreatic cancer cells through proteasome-dependent degradation of IAPs containing the BIR2/3 structural domain.HM90822 inhibits the expression of XIAP and cIAP1/2 proteins in HM822-sensitive Panc-1 and BxPC-3 cells, induces ubiquitylation of IAPs and promotes induces IAP ubiquitination and promotes proteasome-dependent IAP degradation.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    IAP
  • Recptor
    IAP | Apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1363145-46-3
  • Formula Weight
    632.1
  • Molecular Formula
    C30H36ClF2N7O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    N(C=1C2=C(C=C(OC)C(NC(=O)[C@H]3N(C([C@@H](NC([C@@H](NC)C)=O)[C@](C)(C)C)=O)CCC3)=C2)N=CN1)C4=C(F)C(Cl)=C(F)C=C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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