Cart
sales@molnova.com
HAEGTFTSDVS
CAS No. 864915-61-7
HAEGTFTSDVS( —— )
Catalog No. M30081 CAS No. 864915-61-7
HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 374 | Get Quote |
|
| 10MG | 598 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
Biological Information
-
Product NameHAEGTFTSDVS
-
NoteResearch use only, not for human use.
-
Brief DescriptionHAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide.
-
DescriptionHAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide.(In Vitro):The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from intestinal L-cells, in response to the ingestion of food. GLP-1 exerts multiple actions by stimulating insulin secretion from pancreatic β-cells, in a glucose dependent manner (insulinotropic action). GLP-1 lowers circulating plasma glucagon concentration, by inhibiting its secretion (production) from α-cells. GLP-1 also exhibits properties like stimulation of β-cell growth, appetite suppression, delays gastric emptying and stimulation of insulin sensitivity. The peptide analogs of GLP-1 are useful as glucagon-like peptide 1 receptor agonists.
-
In VitroThe GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from intestinal L-cells, in response to the ingestion of food. GLP-1 exerts multiple actions by stimulating insulin secretion from pancreatic β-cells, in a glucose dependent manner (insulinotropic action). GLP-1 lowers circulating plasma glucagon concentration, by inhibiting its secretion (production) from α-cells. GLP-1 also exhibits properties like stimulation of β-cell growth, appetite suppression, delays gastric emptying and stimulation of insulin sensitivity. The peptide analogs of GLP-1 are useful as glucagon-like peptide 1 receptor agonists.
-
In Vivo——
-
Synonyms——
-
PathwayGPCR/G Protein
-
TargetGlucagon Receptor
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number864915-61-7
-
Formula Weight1150.18
-
Molecular FormulaC48H71N13O20
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical NameSequence:His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
US20120264685
molnova catalog
related products
-
Bay 55-9837
Selective VPAC2 receptor agonist (EC50 values are 0.4, 100 and >1000 nM for VPAC2, VPAC1 and PAC1, respectively in a cAMP accumulation assay; IC50 values are 60, 8700 and >10000 nM for VPAC2, VPAC1 and PAC1, respectively in a competition binding assay). Stimulates glucose-dependent insulin secretion in isolated human pancreatic islets. Reduces HIV-1 viral replication and shows cooperative effects when given in conjunction with VPAC1 agonists.
-
NNC 92-1687
NNC 92-1687 is a selective glucagon receptor antagonist that can be used to study type 2 diabetes.
-
Survodutide
Survodutide (BI 456906) is a dual agonist of glucagon and glucagon-like peptide 1 (GLP-1) receptors (GLP Receptor) that reduces body weight in HbA1c16 diabetes.
