Cart
sales@molnova.com
H2L5186303
CAS No. 139262-76-3
H2L5186303( ZINC33388081 )
Catalog No. M27634 CAS No. 139262-76-3
H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 88 | Get Quote |
|
| 10MG | 160 | Get Quote |
|
| 25MG | 357 | Get Quote |
|
| 50MG | 530 | Get Quote |
|
| 100MG | 759 | Get Quote |
|
| 500MG | 1557 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameH2L5186303
-
NoteResearch use only, not for human use.
-
Brief DescriptionH2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.
-
DescriptionH2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.(In Vitro):The high cell invasion activity of HT1080-M6 cells is significantly suppressed by H2L5186303.(In Vivo):H2L5186303 shows strong suppressive efficacy when administered before OVA sensitization and challenge, such as suppression of airway hyper responsiveness, inflammatory cytokine levels, mucin production, and eosinophil numbers.
-
In Vitro——
-
In Vivo——
-
SynonymsZINC33388081
-
PathwayGPCR/G Protein
-
TargetLPA Receptor
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number139262-76-3
-
Formula Weight488.45
-
Molecular FormulaC26H20N2O8
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 250 mg/mL (511.82 mM)
-
SMILESO(C1=CC(OC2=CC=C(NC(/C=C\C(O)=O)=O)C=C2)=CC=C1)C3=CC=C(NC(/C=C\C(O)=O)=O)C=C3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Gibson Francis S. Synthesis of paclitaxel by protecting the 7-?hydroxyl of baccatin III using a strong base and an electrophile. WO9945001A1.
molnova catalog
related products
-
Radioprotectin-1
Radioprotectin-1 is a selective agonist of LPA2 with EC50 of 25 nM for murine LPA2 GPCR and exerts radioprotective and radiomitigative action.
-
LPA2 antagonist 2
LPA2 antagonist 2 is a selective and potent LPA2 antagonist (IC50: 28.3 nM) with potential anticancer activity, inhibits LPA3, and can be used in the study of cancer.
-
Ki16198
Ki16198 is the methyl ester of Ki16425 which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μM.
