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Home - Products - Proteasome/Ubiquitin - Endogenous Metabolite - H-Tyr(3-I)-OH

H-Tyr(3-I)-OH

CAS No. 70-78-0

H-Tyr(3-I)-OH( 3-Iodo-L-tyrosine )

Catalog No. M20288 CAS No. 70-78-0

H-Tyr(3-I)-OH is an inhibitor of tyrosine hydroxylase (Ki = 0.39 M) and an intermediate in the synthesis of thyroid hormones.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    H-Tyr(3-I)-OH
  • Note
    Research use only, not for human use.
  • Brief Description
    H-Tyr(3-I)-OH is an inhibitor of tyrosine hydroxylase (Ki = 0.39 M) and an intermediate in the synthesis of thyroid hormones.
  • Description
    H-Tyr(3-I)-OH is an inhibitor of tyrosine hydroxylase (Ki = 0.39 M) and an intermediate in the synthesis of thyroid hormones.
  • In Vitro
    H-Tyr(3-I)-OH (3-iodo-L-tyrosine) is as effective inhibitor of tyrosine hydroxylase. At a concentration of 100μM 3-iodo-L-tyrosine inhibits the enzymatic activity 100% and at a concentration of 10μM it inhibits 60-70%.
  • In Vivo
    ——
  • Synonyms
    3-Iodo-L-tyrosine
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Human Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    70-78-0
  • Formula Weight
    307.09
  • Molecular Formula
    C9H10INO3
  • Purity
    >98% (HPLC)
  • Solubility
    H2O:6.25 mg/mL (20.35 mM) DMSO:1 mg/mL
  • SMILES
    N[C@@H](Cc1ccc(O)c(I)c1)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Fernández-Espejo Emilio Cristian B H . Excess amounts of 3-iodo-L-tyrosine induce Parkinson-like features in experimental approaches of Parkinsonism[J]. NeuroToxicology 2018:S0161813X18301980-.
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