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Guanadrel

CAS No. 40580-59-4

Guanadrel( —— )

Catalog No. M24365 CAS No. 40580-59-4

Guanadrel is an antihypertensive agent.?

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Guanadrel
  • Note
    Research use only, not for human use.
  • Brief Description
    Guanadrel is an antihypertensive agent.?
  • Description
    Guanadrel is an antihypertensive agent.?
  • In Vitro
    ——
  • In Vivo
    Guanadrel (oral gavage, 15-400 mg/kg, every day, 6-52 weeks) has little toxicity to the nervous system in rats and dogs. Animal Model:Rats, dogs Dosage:15-400 mg/kg Administration:Oral gavage; every day; 6-52 weeks Result:Showed a slight increase in the weight of the prostate and adrenal glands while loss in the kidney in rats.Decreased weight gain values in a dose-dependent manner but liver function is normal in dogs.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    40580-59-4
  • Formula Weight
    213.28
  • Molecular Formula
    C10H19N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (234.43 mM)
  • SMILES
    NC(=N)NCC1COC2(CCCCC2)O1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ming X , Li X , Tang X , et al. N-Hydroxyl derivatives of guanidine based drugs as enzymatic NO donors[J]. Bioorganic & Medicinal Chemistry Letters, 2010, 32(52):no-no.
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