Cart
sales@molnova.com
Groenlandicine
CAS No. 38691-95-1
Groenlandicine ( —— )
Catalog No. M24345 CAS No. 38691-95-1
Groenlandicine is a protoberberine alkaloid from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 426 | In Stock |
|
| 10MG | 611 | In Stock |
|
| 25MG | 888 | In Stock |
|
| 50MG | 1242 | In Stock |
|
| 100MG | 1701 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameGroenlandicine
-
NoteResearch use only, not for human use.
-
Brief DescriptionGroenlandicine is a protoberberine alkaloid from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR).
-
DescriptionGroenlandicine is a protoberberine alkaloid from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR). Groenlandicine selectively induces topoisomerase I-mediated DNA cleavage;Groenlandicine may be a promising anti-Alzheimer's disease agent due to its potent inhibitory activity of both ChEs and beta-amyloids formation, as well as marked ONOO(-) scavenging and good ROS inhibitory capacities.
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetTopoisomerase
-
Recptortopoisomerase I
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number38691-95-1
-
Formula Weight322.3
-
Molecular FormulaC19H16NO4
-
Purity>98% (HPLC)
-
SolubilityDMSO:10 mM
-
SMILESCOC1=CC2=C(C=C1O)CC[N+]3=CC4=C(C=CC5=C4OCO5)C=C23
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Research on bitter components from Coptis chinensis based on electronic tongue.Zhongguo Zhong Yao Za Zhi. 2014 Sep;39(17):3326-9.
molnova catalog
related products
-
(S)-(+)-Camptothecin
An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata.
-
α-Lapachone
alpha-Lapachone has antineoplastic activity, it shows an approximately trypanocidal activity against Trypanosoma cruzi.
-
GW842166X
GW842166X is a potent and highly selective agonist of cannabinoid receptor CB2 receptor with EC50 of 63 nM, shows no significant activity at CB1 receptor. Phase 2.
