Glycitein

CAS No. 40957-83-3

Glycitein( Glycitein | Q-100465 )

Catalog No. M18527 CAS No. 40957-83-3

Glycitein inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 212 In Stock
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Biological Information

  • Product Name
    Glycitein
  • Note
    Research use only, not for human use.
  • Brief Description
    Glycitein inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression.
  • Description
    Glycitein is found in soy and red clover. It exhibits a variety of biological activities, including increasing Nrf2-related antioxidative signaling, preventing invasion in glioma cells destabilizing amyloid-β aggregates and preventing fibril assembly, and inhibiting osteoclast generation.
  • In Vitro
    Cell Viability Assay Cell Line:human gastric cancer cells (AGS, MKN-28, MKN-45, NCI-N87, YCC-1, YCC-6, SNU-5, SNU-216, SNU-484, SNU-668)Concentration:24 h Incubation Time:0-100 μM Result:IC50: 30.98, 60.17, 35.07, 36.05, 33.11, 88.62, 97.68, 83.02, 46.87, 87.55 μM respectively.Apoptosis Analysis Cell Line:AGS cells Concentration:30 μM Incubation Time:3, 6, 12, and 24 hr Result:Increased the expression of Bax, Caspase-3 and cleaved PARP protein, and decreased levels of Bcl-2.
  • In Vivo
    ——
  • Synonyms
    Glycitein | Q-100465
  • Pathway
    Neuroscience
  • Target
    P2 Receptor
  • Recptor
    Others
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    40957-83-3
  • Formula Weight
    284.26
  • Molecular Formula
    C16H12O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (87.95 mM)
  • SMILES
    COC1=C(C=C2C(=C1)C(=O)C(=CO2)C3=CC=C(C=C3)O)O
  • Chemical Name
    7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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