Glutarylcarnitine

CAS No. 102636-82-8

Glutarylcarnitine( —— )

Catalog No. M33601 CAS No. 102636-82-8

Glutarylcarnitine (O-glutaroyl-L-carnitine) is a diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Glutarylcarnitine
  • Note
    Research use only, not for human use.
  • Brief Description
    Glutarylcarnitine (O-glutaroyl-L-carnitine) is a diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes.
  • Description
    Glutarylcarnitine is the diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes.
  • In Vitro
    Malonylcarnitine and Glutarylcarnitine are important diagnostic metabolites in the screening of dried blood spots by tandem mass spectrometry.The urinary excretion of glutarylcarnitine is a specific biochemical marker of glutaric acidemia type I (GA-1). The urinary excretion of glutarylcarnitine is an informative tool in the biochemical diagnosis of glutaric acidemia type I.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    102636-82-8
  • Formula Weight
    275.3
  • Molecular Formula
    C12H21NO6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?Ethanol : 100 mg/mL (363.24 mM; Ultrasonic)DMSO : 2 mg/mL (7.26 mM; Ultrasonic (<60°C)
  • SMILES
    [C@H](OC(CCCC(O)=O)=O)(C[N+](C)(C)C)CC([O-])=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Johnson DW, et al. Stability of malonylcarnitine and Glutarylcarnitine in stored blood spots. J Inherit Metab Dis. 2004;27(6):789-90.?
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