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Givinostat
CAS No. 732302-99-7
Givinostat ( ITF2357 )
Catalog No. M15799 CAS No. 732302-99-7
Givinostat hydrochloride monohydrate is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 65 | In Stock |
|
| 10MG | 115 | In Stock |
|
| 25MG | 228 | In Stock |
|
| 50MG | 417 | In Stock |
|
| 100MG | 615 | In Stock |
|
| 500MG | 1305 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGivinostat
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NoteResearch use only, not for human use.
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Brief DescriptionGivinostat hydrochloride monohydrate is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively.
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DescriptionGivinostat hydrochloride monohydrate is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively.
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SynonymsITF2357
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorHD1-A; HD1-B; HD2
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number732302-99-7
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Formula Weight475.97
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Molecular FormulaCHClNO
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Purity>98%(HPLC)
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SolubilityDMSO:95 mg/mL (199.59 mM); Ethanol:3 mg/mL (6.3 mM); Water:<1 mg/mL (<1 mM)
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SMILESO=C(OCC1=CC=C2C=C(CN(CC)CC)C=CC2=C1)NC3=CC=C(C(NO)=O)C=C3.[H]Cl.O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Li S, et al. Specific inhibition of histone deacetylase 8 reduces gene expression and production of proinflammatory cytokines in vitro and in vivo. J Biol Chem. 2015 Jan 23;290(4):2368-78.
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