Geraniin

CAS No. 60976-49-0

Geraniin( —— )

Catalog No. M18888 CAS No. 60976-49-0

Geraniin has a protective effect against OVX-induced rat osteoporosis.Geraniin has cytotoxic activity towards cancer cells in vitro and in vivo.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 65 In Stock
10MG 110 In Stock
25MG 177 In Stock
50MG 267 In Stock
100MG 408 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Geraniin
  • Note
    Research use only, not for human use.
  • Brief Description
    Geraniin has a protective effect against OVX-induced rat osteoporosis.Geraniin has cytotoxic activity towards cancer cells in vitro and in vivo.
  • Description
    Geraniin has a protective effect against OVX-induced rat osteoporosis. Geraniin has cytotoxic activity towards cancer cells in vitro and in vivo. Geraniin exerts inhibitory effects on osteoclast differentiation in vitro and suppresses Ti particle-induced osteolysis in vivo, is a potential natural compound for the treatment of wear particle induced osteolysis in prostheses failure. Geraniin has anti-oxidant activity, induces Nrf2-mediated expression of antioxidant enzymes HO-1 and NQO1, presumably via PI3K/AKT and ERK1/2 signaling pathways, thereby protecting cells from H2O2-induced oxidative cell death. Geraniin presents radioprotective effects by regulating DNA damage on splenocytes, exerting immunostimulatory capacities and inhibiting apoptosis of radiosensitive immune cells and jejunal crypt cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    Aromatase
  • Recptor
    Antioxidant
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    60976-49-0
  • Formula Weight
    952.64
  • Molecular Formula
    C41H28O27
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 100 mg/mL 104.97 mM;
  • SMILES
    C1C2C3C(C(C(O2)OC(=O)C4=CC(=C(C(=C4)O)O)O)OC(=O)C5=CC(=C(C6=C5C7C(=CC(=O)C(C7(O)O)(O6)O)C(=O)O3)O)O)OC(=O)C8=CC(=C(C(=C8C9=C(C(=C(C=C9C(=O)O1)O)O)O)O)O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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    Geraniin has a protective effect against OVX-induced rat osteoporosis.Geraniin has cytotoxic activity towards cancer cells in vitro and in vivo.