Gentiopicrin ( O673; O-673; O 673; SC-46058 )

Catalog No. M18227 CAS No. 20831-76-9

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Product Name

Gentiopicrin
Note

Research use only, not for human use.
Brief Description

Gentiopicroside, a naturally occurring iridoid glycoside, extracted from Gentiana manshurica Kitag, inhibits P450 activity, with an IC50 and a Ki of 61 μM and 22.8 μM for CYP2A6.
Description

Gentiopicrin is found in gentiana and cephalaria. It displays many biological properties, including suppressing expression of NMDA receptors in the anterior cingulate cortex, inhibiting morphine conditioned place preference, and preventing arachidonic acid and PMA-induced superoxide generation.
Synonyms

O673; O-673; O 673; SC-46058
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Others-Field
Indication

——

CAS Number

20831-76-9
Formula Weight

356.33
Molecular Formula

C16H20O9
Purity

98%
Solubility

DMSO : ≥ 150 mg/mL; 420.97 mM
SMILES

C=C[C@H]1[C@@H](OC=C2C1=CCOC2=O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O
Chemical Name

(5R,6S)-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-5-vinyl-5,6-dihydro-1H,3H-pyrano[3,4-c]pyran-1-one

1. Zhang K, et al. Int J Nanomedicine. 2013;8:3227-39.

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