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Gamma-Methylleucine
CAS No. 57224-50-7
Gamma-Methylleucine ( gamma-Methyl-L-leucine; L-Neopentylglycine; 2-Amino-3-tert-butylpropionic acid )
Catalog No. M27985 CAS No. 57224-50-7
Gamma-Methylleucine is an auxiliary for copper-catalyzed asymmetric Michael reactions.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 47 | Get Quote |
|
| 100MG | 71 | Get Quote |
|
| 200MG | 106 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameGamma-Methylleucine
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NoteResearch use only, not for human use.
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Brief DescriptionGamma-Methylleucine is an auxiliary for copper-catalyzed asymmetric Michael reactions.
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DescriptionGamma-Methylleucine is an auxiliary for copper-catalyzed asymmetric Michael reactions.(In Vivo):gamma-Methylleucine improved the binding affinity of the peptide for Y2R but also increased its anorectic activity in lean mice . Gamma-methylleucine resulted in loss of or significantly decreased the biological activity of ET-1, while high affinity for the ETA (IC50 = 0.42-0.70 nM) and ETB (IC50 = 0.17-0.43 nM) receptor was retained . Gamma-methylleucine was shown to have high antagonist activitiesin Sarafotoxin S6c-induced vasoconstriction of rabbit pulmonary artery (ET-1: pA2 8.4) and have the desirable characteristic of possessing no agonist activity at either receptor subtype .
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Synonymsgamma-Methyl-L-leucine; L-Neopentylglycine; 2-Amino-3-tert-butylpropionic acid
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number57224-50-7
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Formula Weight145.2
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Molecular FormulaC7H15NO2
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(C)(C)C[C@H](N)C(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Son MJ, et al. A novel and safe small molecule enhances hair follicle regeneration by facilitating metabolic reprogramming. Exp Mol Med. 2018 Dec 6;50(12):160.
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