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GSK270822A
CAS No. 864082-23-5
GSK270822A( —— )
Catalog No. M34271 CAS No. 864082-23-5
GSK270822A is a selective ROCK1 inhibitor. GSK270822A exhibits IC50 of 9nM, 1100nM, 1550nM for ROCK1, RSK1, p70S6K, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 362 | Get Quote |
|
| 5MG | 553 | Get Quote |
|
| 10MG | 735 | Get Quote |
|
| 25MG | 1076 | Get Quote |
|
| 50MG | 1444 | Get Quote |
|
| 100MG | 1899 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameGSK270822A
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NoteResearch use only, not for human use.
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Brief DescriptionGSK270822A is a selective ROCK1 inhibitor. GSK270822A exhibits IC50 of 9nM, 1100nM, 1550nM for ROCK1, RSK1, p70S6K, respectively.
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DescriptionRho-Kinase-IN-3 (compound 12) is a potent and selective Rho kinase (ROCK1) inhibitor with an IC50 value of 8 nM. Rho-Kinase-IN-3 can be used in research of hypertension.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetGRK (GPCRK)
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RecptorGRK
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Research Area——
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Indication——
Chemical Information
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CAS Number864082-23-5
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Formula Weight396.44
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Molecular FormulaC24H20N4O2
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Purity>98% (HPLC)
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Solubility——
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SMILESC(NC=1C=C2C(=CC1)NN=C2)(=O)C=3C(CC(=O)NC3C)C4=CC5=C(C=C4)C=CC=C5
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Goodman KB, et, al. Development of dihydropyridone indazole amides as selective Rho-kinase inhibitors. J Med Chem. 2007 Jan 11;50(1):6-9.?
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GSK270822A
GSK270822A is a selective ROCK1 inhibitor. GSK270822A exhibits IC50 of 9nM, 1100nM, 1550nM for ROCK1, RSK1, p70S6K, respectively.
