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GSK2334470

CAS No. 1227911-45-6

GSK2334470( GSK2334470 | GSK 2334470 | GSK-2334470 )

Catalog No. M10881 CAS No. 1227911-45-6

GSK2334470 is a novel PDK1 inhibitor with IC50 of ~10 nM in a cell-free assay.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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25MG 133 Get Quote
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Biological Information

  • Product Name
    GSK2334470
  • Note
    Research use only, not for human use.
  • Brief Description
    GSK2334470 is a novel PDK1 inhibitor with IC50 of ~10 nM in a cell-free assay.
  • Description
    GSK2334470 is a novel PDK1 inhibitor with IC50 of ~10 nM in a cell-free assay, with no activity at other close related AGC-kinases.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    GSK2334470 | GSK 2334470 | GSK-2334470
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    PDK
  • Recptor
    PDK1
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1227911-45-6
  • Formula Weight
    462.59
  • Molecular Formula
    C25H34N8O
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 90 mg/mL (194.55 mM); DMSO: 90 mg/mL (194.55 mM)
  • SMILES
    O=C([C@@H]1CN(C2=NC(NC)=NC(C3=CC4=C(C=C3)C(N)=NN4)=C2)[C@H](C)CC1)NC5CCCCC5
  • Chemical Name
    (3S,6R)-1-(6-(3-amino-1H-indazol-6-yl)-2-(methylamino)pyrimidin-4-yl)-N-cyclohexyl-6-methylpiperidine-3-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Najafov A, et al. Biochem J, 2011, 433(2), 357-369.
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