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KPLH1130
CAS No. 906669-07-6
KPLH1130( —— )
Catalog No. M24944 CAS No. 906669-07-6
KPLH1130 improves glucose tolerance in HFD-fed mice. KPLH1130 is a specific pyruvate dehydrogenase kinase (PDK) inhibitor, blocks macrophage polarization and attenuates proinflammatory responses.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 205 | In Stock |
|
| 10MG | 332 | In Stock |
|
| 25MG | 560 | In Stock |
|
| 50MG | 797 | In Stock |
|
| 100MG | 1071 | In Stock |
|
| 500MG | 2187 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameKPLH1130
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NoteResearch use only, not for human use.
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Brief DescriptionKPLH1130 improves glucose tolerance in HFD-fed mice. KPLH1130 is a specific pyruvate dehydrogenase kinase (PDK) inhibitor, blocks macrophage polarization and attenuates proinflammatory responses.
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DescriptionKPLH1130 improves glucose tolerance in HFD-fed mice. KPLH1130 is a specific pyruvate dehydrogenase kinase (PDK) inhibitor, blocks macrophage polarization and attenuates proinflammatory responses.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayPI3K/Akt/mTOR signaling
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TargetPDK
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RecptorPDK
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Research Area——
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Indication——
Chemical Information
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CAS Number906669-07-6
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Formula Weight283.28
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Molecular FormulaC15H13N3O3
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Purity>98% (HPLC)
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SolubilityDMSO:130 mg/mL (458.91 mM; Need ultrasonic)
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SMILESO=C1NN=C(C2=CC=C(O)C=C2O)N1C3=CC=C(C)C=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Min BK, et al. Pyruvate Dehydrogenase Kinase Is a Metabolic Checkpoint for Polarization of Macrophages to the M1 Phenotype. Front Immunol. 2019 May 7;10:944.
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