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Home - Products - Membrane Transporter/Ion Channel - TRP/TRPV Channel - GSK2193874

GSK2193874

CAS No. 1336960-13-4

GSK2193874 ( —— )

Catalog No. M20323 CAS No. 1336960-13-4

GSK2193874 was identified as a selective orally active TRPV4 blocker.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 67 In Stock
10MG 116 In Stock
25MG 233 In Stock
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Biological Information

  • Product Name
    GSK2193874
  • Note
    Research use only not for human use.
  • Brief Description
    GSK2193874 was identified as a selective orally active TRPV4 blocker.
  • Description
    GSK2193874 was identified as a selective orally active TRPV4 blocker.
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    TRP/TRPV Channel
  • Recptor
    TRPV4
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1336960-13-4
  • Formula Weight
    691.6
  • Molecular Formula
    C37H38BrF3N4O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL?(144.59 mM)
  • SMILES
    FC(F)(F)c1cccc(c1)-c1nc2cc(Br)ccc2c(C(=O)NC2(CC2)c2ccccc2)c1CN1CCC(CC1)N1CCCCC1
  • Chemical Name
    7-bromo-N-(1-phenylcyclopropyl)-3-[(4-piperidin-1-ylpiperidin-1-yl) methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Cheung M Bao W Behm D J et al. Discovery of GSK2193874: An Orally Active Potent and Selective Blocker of Transient Receptor Potential Vanilloid 4[J]. ACS Medicinal Chemistry Letters 2017:acsmedchemlett.7b00094.
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