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GSK189254A
CAS No. 720690-73-3
GSK189254A ( GSK189254 )
Catalog No. M24731 CAS No. 720690-73-3
GSK189254A is a potent and specific histamine H3 receptor antagonist (pKi values: 9.59-9.90 and 8.51-9.17 for human and rat H3).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 77 | In Stock |
|
| 10MG | 113 | In Stock |
|
| 50MG | 332 | In Stock |
|
| 100MG | 478 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGSK189254A
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NoteResearch use only, not for human use.
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Brief DescriptionGSK189254A is a potent and specific histamine H3 receptor antagonist (pKi values: 9.59-9.90 and 8.51-9.17 for human and rat H3).
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DescriptionGSK189254A is a potent and specific histamine H3 receptor antagonist (pKi values: 9.59-9.90 and 8.51-9.17 for human and rat H3).
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SynonymsGSK189254
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PathwayGPCR/G Protein
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TargetHistamine Receptor
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RecptorMouse H3 receptor;Human H3 receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number720690-73-3
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Formula Weight351.4
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Molecular FormulaC21H25N3O2
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Purity>98% (HPLC)
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SolubilityDMSO:24 mg/mL (68.29 mM; Need ultrasonic)
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SMILESCNC(=O)C1=CN=C(C=C1)OC2=CC3=C(CCN(CC3)C4CCC4)C=C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Medhurst AD, et al. GSK189254, a novel H3 receptor antagonist that binds to histamine H3 receptors in Alzheimer's disease brain and improves cognitive performance in preclinical models. J Pharmacol Exp Ther. 2007 Jun;321(3):1032-45.
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