MK-7288
CAS No. 936626-07-2
MK-7288 ( MK7288;MK 7288 )
Catalog No. M16708 CAS No. 936626-07-2
A novel histamine H3 receptor inverse agonist for the treatment of sleep apnoea syndrome.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 873 | Get Quote |
|
50MG | 1782 | Get Quote |
|
100MG | 2250 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameMK-7288
-
NoteResearch use only, not for human use.
-
Brief DescriptionA novel histamine H3 receptor inverse agonist for the treatment of sleep apnoea syndrome.
-
DescriptionA novel histamine H3 receptor inverse agonist for the treatment of sleep apnoea syndrome; significantly prolongs MWT sleep latency, and improves car driving simulation standard deviation of lane position in clinical trials.Sleep Disorder Phase 1 Clinical
-
SynonymsMK7288;MK 7288
-
PathwayGPCR/G Protein
-
TargetHistamine Receptor
-
RecptorHistamine Receptor
-
Research AreaNeurological Disease
-
IndicationSleep Disorder
Chemical Information
-
CAS Number936626-07-2
-
Formula Weight401.51
-
Molecular FormulaC22H31N3O4
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCN(CCN1CCCCC1)C(=O)C2CCC3(CC2)C4=C(C(=O)O3)N=C(C=C4)OC
-
Chemical Name(1r,4r)-2'-methoxy-N-methyl-7'-oxo-N-(2-(piperidin-1-yl)ethyl)-7'H-spiro[cyclohexane-1,5'-furo[3,4-b]pyridine]-4-carboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Sun H, et al. J Clin Pharmacol. 2013 Dec;53(12):1294-302.
molnova catalog
related products
-
GSK-239512
GSK-239512 is an antagonist of H3 receptor and can be used in studies about the treatment of cognitive dysfunction in neurodegenerative disorders.
-
JNJ-5207852 dihydroc...
JNJ-5207852 is a novel, non-imidazole histamine H3 receptor antagonist, with high affinity at the rat (pKi=8.9) and human (pKi=9.24) H3 receptor. JNJ-5207852 is a potent dibasic amine antagonist that binds potently to rat H3 receptors (Ki=1.2?nm), and has good brain penetration. In ex vivo binding studies in mice, the compound had an ED50 of 0.13?mg?kg?1, subcutaneously.
-
Tanshinone IIA
Tanshinone IIA(Tanshinone B) is the diterpene quinone in Danshen, which is utilized in the treatment of cardiovascular and inflammatory.