GSK-812( GSK812 )

Catalog No. M15383 CAS No. 630407-66-8

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

GSK-812
Note

Research use only, not for human use.
Brief Description

GSK-812 is a potent neuroprotectant that can induce GDNF in normal and diseased retina.
Description

GSK-812 is a potent neuroprotectant that can induce GDNF in normal and diseased retina, shows has polypharmacology antagonizing multiple receptors, including D2 and D3 receptors, and 5-HT2A, 2C, and 5-HT6 receptors.
In Vitro

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In Vivo

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Synonyms

GSK812
Pathway

Endocrinology/Hormones
Target

5-HT Receptor
Recptor

5-HT Receptor
Research Area

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Indication

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CAS Number

630407-66-8
Formula Weight

471.996
Molecular Formula

C25H26ClNO4S
Purity

>98% (HPLC)
Solubility

——
SMILES

CN1CCC2=CC(=C(C=C2CC1)S(=O)(=O)C3=CC=C(C=C3)OCC4=CC=C(C=C4)Cl)OC
Chemical Name

7-[4-(4-chloro-benzyloxy)-benzenesulfonyl]-8-methoxy-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine

1. Baranov P, et al. J Ocul Pharmacol Ther. 2017 Jun;33(5):412-422.

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