Cart
sales@molnova.com
Home - Products - GPCR/G Protein - Antibacterial - GSK-2140944

GSK-2140944

CAS No. 1075236-89-3

GSK-2140944 ( Gepotidacin;GSK2140944 )

Catalog No. M10308 CAS No. 1075236-89-3

GSK-2140944 (Gepotidacin) is a novel potent, selective bacterial type II topoisomerase inhibitor in development for the treatment of conventional and biothreat pathogens.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 328 Get Quote
50MG 1746 Get Quote
100MG 2502 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    GSK-2140944
  • Note
    Research use only, not for human use.
  • Brief Description
    GSK-2140944 (Gepotidacin) is a novel potent, selective bacterial type II topoisomerase inhibitor in development for the treatment of conventional and biothreat pathogens.
  • Description
    GSK-2140944 (Gepotidacin) is a novel potent, selective bacterial type II topoisomerase inhibitor in development for the treatment of conventional and biothreat pathogens, including Gram-positive pathogens and MRSA; shows antibacterial activity against MSSA and MRSA isolates (MIC90=0.5 ug/ml).Bacterial Infection Phase 2 Clinical
  • Synonyms
    Gepotidacin;GSK2140944
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    Infection
  • Indication
    Bacterial Infection

Chemical Information

  • CAS Number
    1075236-89-3
  • Formula Weight
    448.53
  • Molecular Formula
    C24H28N6O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 7.14 mg/mL 15.92 mM
  • SMILES
    O=C(C=NC(C=C1)=C23)N3[C@H](CN4CCC(NCC(N=C5)=CC6=C5OCCC6)CC4)CN2C1=O
  • Chemical Name
    (2R)-2-[[4-[[(3,4-Dihydro-2H-pyrano[2,3-c]pyridin-6-yl)methyl]amino]-1-piperidinyl]methyl]-1,2-dihydro-3H,8H-2a,5,8a-triazaacenaphthylene-3,8-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bax BD, et al. Nature. 2010 Aug 19;466(7309):935-40.
2. Biedenbach DJ, et al. Antimicrob Agents Chemother. 2016 Jan 4;60(3):1918-23.
3. So W, et al. Antimicrob Agents Chemother. 2015 Aug;59(8):4956-61.
4. Farrell DJ, et al. Antimicrob Agents Chemother. 2017 Feb 23;61(3). pii: e02047-16.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Apramycin sulfate

    Apramycin sulfate is an aminoglycoside antibiotic mproduced by a strain of Streptomyces tenebrarius, used in veterinary practice.

  • Nifuratel

    Nifuratel(NF 113, SAP 113) is a broad antibacterial spectrum agent, which is used as an antibacterial, antifungal, and antiprotozoal (Trichomonas).

  • ABMA

    ABMA is a novel broad-spectrum inhibitor of intracellular toxins and pathogens, efficiently protects cells against various toxins and pathogens including viruses, intracellular bacteria and parasite.

Sign In Join Free