GSK-1520489A

CAS No. 1042433-41-9

GSK-1520489A( —— )

Catalog No. M28990 CAS No. 1042433-41-9

GSK-1520489A is an active PKMYT1 inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 192 Get Quote
10MG 312 Get Quote
25MG 530 Get Quote
50MG 758 Get Quote
100MG 1044 Get Quote
500MG 2097 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    GSK-1520489A
  • Note
    Research use only, not for human use.
  • Brief Description
    GSK-1520489A is an active PKMYT1 inhibitor.
  • Description
    GSK-1520489A is an active PKMYT1 inhibitor.
  • In Vitro
    GSK-1520489A (4 μM, 24 h) treatment shows inhibition of phosphorylation of Tyr15 in Cdk1. Western Blot Analysis Cell Line:HT29 cells Concentration:4 μM Incubation Time:24 hours Result:Reduced Cdk1-phosphorylation at tyrosine in comparison to the uninhibited reaction.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    MCT4
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1042433-41-9
  • Formula Weight
    538.53
  • Molecular Formula
    C21H23N4O7PS2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 35.71 mg/mL (83.92 mM)
  • SMILES
    CC(C)(C)S(c1cc2c(Nc(cc3)cc4c3scn4)ncnc2cc1OCCOP(O)(O)=O)(=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Cluntun AA, et.al. The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure. Cell Metab. 2021 Mar 2;33(3):629-648.e10.
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