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GSK-1322322

CAS No. 1152107-25-9

GSK-1322322 ( Lanopepden;GSK-322 )

Catalog No. M10536 CAS No. 1152107-25-9

A novel antibacterial agent that targets bacterial peptide deformylase; demonstrates in vitro activity against MDR respiratory and skin infection pathogens.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    GSK-1322322
  • Note
    Research use only, not for human use.
  • Brief Description
    A novel antibacterial agent that targets bacterial peptide deformylase; demonstrates in vitro activity against MDR respiratory and skin infection pathogens.
  • Description
    A novel antibacterial agent that targets bacterial peptide deformylase; demonstrates in vitro activity against MDR respiratory and skin infection pathogens, including MDR Streptococcus pneumoniae and MRSA; inhibits S. pneumoniae ATCC 49619 with MIC of 0.12-0.5 ug/mL.
  • Synonyms
    Lanopepden;GSK-322
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    1152107-25-9
  • Formula Weight
    479.56
  • Molecular Formula
    C22H34FN7O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1=NC(=C(C(=N1)N2CCN3CCOCC3C2)F)NNC(=O)C(CC4CCCC4)CN(C=O)O
  • Chemical Name
    N-((R)-2-(cyclopentylmethyl)-3-(2-(5-fluoro-6-((S)-hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl)-2-methylpyrimidin-4-yl)hydrazinyl)-3-oxopropyl)-N-hydroxyformamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ross JE, et al. J Clin Microbiol. 2011 Nov;49(11):3928-30.
2. Arat S, et al. Antimicrob Agents Chemother. 2015 Feb;59(2):1182-92.
3. O'Dwyer K, et al. Antimicrob Agents Chemother. 2013 May;57(5):2333-42.
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