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GSA-10
CAS No. 300833-95-8
GSA-10( —— )
Catalog No. M27632 CAS No. 300833-95-8
GSA-10 is a potent Smoothened (Smo) receptor agonist with an EC50 of 1.2 μM. It acts on Smo to promote the differentiation of pluripotent mesenchymal stem cells into osteoblasts.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 177 | Get Quote |
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| 5MG | 282 | Get Quote |
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| 10MG | 421 | Get Quote |
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| 25MG | 678 | Get Quote |
|
| 50MG | 888 | Get Quote |
|
| 100MG | 1251 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameGSA-10
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NoteResearch use only, not for human use.
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Brief DescriptionGSA-10 is a potent Smoothened (Smo) receptor agonist with an EC50 of 1.2 μM. It acts on Smo to promote the differentiation of pluripotent mesenchymal stem cells into osteoblasts.
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DescriptionGSA-10 is a potent Smoothened (Smo) receptor agonist with an EC50 of 1.2 μM. It acts on Smo to promote the differentiation of pluripotent mesenchymal stem cells into osteoblasts. It also mediates Hedgehog (Hh) signaling, which may have research implications for regenerative medicine in cancer diseases.
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In VitroWestern Blot Analysis Cell Line:3T3-L1 preadipocyte Concentration:10 μM Incubation Time: 24 h Result:Significantly promoted the phosphorylation of Ampk.
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetHedgehog (Hh)
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number300833-95-8
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Formula Weight450.535
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Molecular FormulaC26H30N2O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 1.67 mg/mL (3.71 mM)
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SMILESCCCCCCn1c2ccccc2c(O)c(C(=O)Nc2ccc(cc2)C(=O)OCCC)c1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Di Maio F, et al. Activity of creatinol O-phosphate on persistent ventricular premature beats in ischemic heart disease. Double blind clinical trial. Arzneimittelforschung. 1979;29(9a):1488-1490.
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