GS-9191

CAS No. 859209-84-0

GS-9191( —— )

Catalog No. M34081 CAS No. 859209-84-0

GS-9191 is a potent inhibitor of DNA polymerase alpha and ? , a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG) , which penetrates the skin and is metabolized in the epithelium to an active nucleoside triphosphate analogue.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 274 Get Quote
5MG 428 Get Quote
10MG 630 Get Quote
25MG 908 Get Quote
50MG 1279 Get Quote
100MG 1692 Get Quote
500MG 3411 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    GS-9191
  • Note
    Research use only, not for human use.
  • Brief Description
    GS-9191 is a potent inhibitor of DNA polymerase alpha and ? , a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG) , which penetrates the skin and is metabolized in the epithelium to an active nucleoside triphosphate analogue.
  • Description
    GS-9191 is a potent inhibitor of DNA polymerase alpha and ? , a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG) , which penetrates the skin and is metabolized in the epithelium to an active nucleoside triphosphate analogue.GS-9191 has antiproliferative activity and reduces the size of papillomas in a dose-related manner.GS-9191 may be useful in the treatment of HPV-induced lesions.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    DNA/RNA Synthesis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    859209-84-0
  • Formula Weight
    734.82
  • Molecular Formula
    C37H51N8O6P
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(COCP(N[C@@H](CC1=CC=CC=C1)C(OCC(C)C)=O)(N[C@@H](CC2=CC=CC=C2)C(OCC(C)C)=O)=O)N3C=4C(=C(NC5CC5)N=C(N)N4)N=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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