GRK5-IN-2

CAS No. 1642839-27-7

GRK5-IN-2( —— )

Catalog No. M28800 CAS No. 1642839-27-7

GRK5-IN-2, a pyridine-based bicyclic compound, is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor. It regulates the expression and/or release of insulin and is useful for the metabolic disease research.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 68 Get Quote
10MG 110 Get Quote
25MG 222 Get Quote
50MG 357 Get Quote
100MG 530 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    GRK5-IN-2
  • Note
    Research use only, not for human use.
  • Brief Description
    GRK5-IN-2, a pyridine-based bicyclic compound, is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor. It regulates the expression and/or release of insulin and is useful for the metabolic disease research.
  • Description
    GRK5-IN-2, a pyridine-based bicyclic compound, is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor. It regulates the expression and/or release of insulin and is useful for the metabolic disease research.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    GRK (GPCRK)
  • Recptor
    NPY Y2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1642839-27-7
  • Formula Weight
    380.4
  • Molecular Formula
    C20H20N4O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 62.5 mg/mL (164.30 mM)
  • SMILES
    Cn1c(-c2ccco2)nc2c1cc(Nc(cc1OC)cc(OC)c1OC)nc2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Domin H, et al. Characterization of the Brain Penetrant Neuropeptide Y Y2 Receptor Antagonist SF-11. ACS Chem Neurosci. 2019;10(8):3454-3463.
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