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GDC-0994
CAS No. 1453848-26-4
GDC-0994 ( RG-7842 )
Catalog No. M11952 CAS No. 1453848-26-4
GDC-0994 is a potent, orally available ERK1/2 inhibitor with IC50 of 1.1 nM and 0.3 nM, respectively. Phase 1.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 42 | In Stock |
|
| 5MG | 69 | In Stock |
|
| 10MG | 87 | In Stock |
|
| 25MG | 158 | In Stock |
|
| 50MG | 267 | In Stock |
|
| 100MG | 399 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGDC-0994
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NoteResearch use only, not for human use.
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Brief DescriptionGDC-0994 is a potent, orally available ERK1/2 inhibitor with IC50 of 1.1 nM and 0.3 nM, respectively. Phase 1.
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DescriptionGDC-0994 is a potent, orally available ERK1/2 inhibitor with IC50 of 1.1 nM and 0.3 nM, respectively. Phase 1.
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SynonymsRG-7842
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PathwayMAPK/ERK Signaling
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TargetERK
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RecptorERK1; ERK2
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1453848-26-4
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Formula Weight440.86
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Molecular FormulaC21H18ClFN6O2
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Purity>98%(HPLC)
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SolubilityEthanol: 87 mg/mL (197.79 mM); DMSO: 87 mg/mL (197.79 mM)
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SMILESO=C1C=C(C2=NC(NC3=CC=NN3C)=NC=C2)C=CN1[C@@H](C4=CC=C(Cl)C(F)=C4)CO
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Chemical Name(S)-1-(1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. AACR2014. Abstract.
molnova catalog
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