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GATA4-IN-3
CAS No. 544681-96-1
GATA4-IN-3( GATA4 inhibitor 3 )
Catalog No. M14956 CAS No. 544681-96-1
A novel small molecule that inhibits GATA4/NKX2-5 transcriptional synergy with IC50 of 3 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 205 | Get Quote |
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| 10MG | 335 | Get Quote |
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| 25MG | 566 | Get Quote |
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| 50MG | 806 | Get Quote |
|
| 100MG | 1098 | Get Quote |
|
| 500MG | 2205 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameGATA4-IN-3
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NoteResearch use only, not for human use.
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Brief DescriptionA novel small molecule that inhibits GATA4/NKX2-5 transcriptional synergy with IC50 of 3 uM.
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DescriptionA novel small molecule that inhibits GATA4/NKX2-5 transcriptional synergy with IC50 of 3 uM, with no activity on the protein kinases involved in the regulation of GATA4 phosphorylation; also inhibits the ET-1-stimulated BNP gene expression, and inhibits hypertrophic growth in a cardiomyocyte hypertrophy model, without effect on apoptotic cell death.
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In Vitro——
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In Vivo——
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SynonymsGATA4 inhibitor 3
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PathwayNuclear Receptor/Transcription Factor
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TargetGATA Binding Protein
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RecptorGATA Binding Protein
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Research Area——
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Indication——
Chemical Information
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CAS Number544681-96-1
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Formula Weight349.434
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Molecular FormulaC21H23N3O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 83.33 mg/mL (238.47 mM)
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SMILESCC1=C(C(NC2=CC=C(N(CC)CC)C=C2)=O)C(C3=CC=CC=C3)=NO1
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Chemical NameN-[4-(diethylamino)phenyl]-5-methyl-3-phenylisoxazole-4-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. V?lim?ki MJ, et al. J Med Chem. 2017 Sep 28;60(18):7781-7798.
molnova catalog
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GATA4-IN-3
A novel small molecule that inhibits GATA4/NKX2-5 transcriptional synergy with IC50 of 3 uM.
