Fluocinonide( NSC 101791 )

Catalog No. M14220 CAS No. 356-12-7

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Product Name

Fluocinonide
Note

Research use only, not for human use.
Brief Description

Fluocinonide (Vanos) is a potent glucocorticoid steroid used topically as anti-inflammatory agent for the treatment of skin disorders such as eczema.
Description

Fluocinonide (Vanos) is a potent glucocorticoid steroid used topically as anti-inflammatory agent for the treatment of skin disorders such as eczema.
In Vitro

——
In Vivo

——
Synonyms

NSC 101791
Pathway

Endocrinology/Hormones
Target

GR
Recptor

Glucocorticoid Receptor
Research Area

Inflammation/Immunology
Indication

——

CAS Number

356-12-7
Formula Weight

494.52
Molecular Formula

C26H32F2O7
Purity

>98% (HPLC)
Solubility

DMSO: 99 mg/mL (200.19 mM)
SMILES

CC(OCC([C@@]12[C@H](OC(C)(C)O2)C[C@@H]3[C@]1(C)C[C@H](O)[C@@]4(F)[C@H]3C[C@H](F)C5=CC(C=C[C@@]54C)=O)=O)=O
Chemical Name

2-((2S,6aS,6bR,7S,8aS,8bS,11aR,12aS,12bS)-2,6b-difluoro-7-hydroxy-6a,8a,10,10-tetramethyl-4-oxo-2,4,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoethyl acetate

1.Gans EH, et al. J Drugs Dermatol, 2008, 7(1), 28-32.

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