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Cortodoxone

CAS No. 152-58-9

Cortodoxone( 11-Deoxycortisol | Cortexolone )

Catalog No. M12133 CAS No. 152-58-9

Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Cortodoxone
  • Note
    Research use only, not for human use.
  • Brief Description
    Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone).
  • Description
    Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone); exhibits corticosteroid binding characteristics, including DNA binding; 11-deoxycortisol is regulated by the hypothalamus-pituitary axis and responded to acute stress; impedes GABAergic neurotransmission and induces drug-resistant status epilepticus in mice.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    11-Deoxycortisol | Cortexolone
  • Pathway
    Endocrinology/Hormones
  • Target
    GR
  • Recptor
    GlucocorticoidReceptor
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    152-58-9
  • Formula Weight
    346.4605
  • Molecular Formula
    C21H30O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 33 mg/mL
  • SMILES
    CC12CCC(=O)C=C1CCC3C2CCC4(C3CCC4(C(=O)CO)O)C
  • Chemical Name
    Pregn-4-ene-3,20-dione, 17,21-dihydroxy-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Close DA, et al. Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13942-7. 2. Kaminski RM, et al. Neuropharmacology. 2011 Jun;60(7-8):1098-108. 3. Baker ME, et al. Steroids. 2011 Dec 11;76(13):1451-7.
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