Flumethasone( NSC 5402 | NSC 54702 | U-10974 )

Catalog No. M13401 CAS No. 2135-17-3

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Product Name

Flumethasone
Note

Research use only, not for human use.
Brief Description

Flumethasone is a glucocorticoid receptor agonist, this complex binds to the nucleus causing a variety of genetic activation and repressions.
Description

Flumethasone is a glucocorticoid receptor agonist, this complex binds to the nucleus causing a variety of genetic activation and repressions.
In Vitro

——
In Vivo

——
Synonyms

NSC 5402 | NSC 54702 | U-10974
Pathway

Endocrinology/Hormones
Target

GR
Recptor

Glucocorticoid Receptor
Research Area

Inflammation/Immunology
Indication

——

CAS Number

2135-17-3
Formula Weight

410.46
Molecular Formula

C22H28F2O5
Purity

>98% (HPLC)
Solubility

Ethanol: 6 mg/mL (14.61 mM); DMSO: 82 mg/mL (199.78 mM)
SMILES

O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@]4(C)[C@](C(CO)=O)(O)[C@H](C)C[C@@]4([H])[C@]3([H])C[C@H](F)C2=C1
Chemical Name

(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

1.Sternbauer K, et al. Zentralbl Veterinarmed A, 1998, 45(6-7), 441-443.

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