
Flovagatran
CAS No. 871576-03-3
Flovagatran( —— )
Catalog No. M34600 CAS No. 871576-03-3
Flovagatran (TGN 255) is an orally active, potent, and selective inhibitor of thrombin and parenteral direct factor II.Flovagatran is used to study venous thromboembolism.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 1158 | Get Quote |
![]() ![]() |
5MG | 1511 | Get Quote |
![]() ![]() |
10MG | 1881 | Get Quote |
![]() ![]() |
50MG | 2374 | Get Quote |
![]() ![]() |
500MG | Get Quote | Get Quote |
![]() ![]() |
1G | Get Quote | Get Quote |
![]() ![]() |
Biological Information
-
Product NameFlovagatran
-
NoteResearch use only, not for human use.
-
Brief DescriptionFlovagatran (TGN 255) is an orally active, potent, and selective inhibitor of thrombin and parenteral direct factor II.Flovagatran is used to study venous thromboembolism.
-
DescriptionFlovagatran (TGN 255) is a potent and reversible thrombin inhibitor (Ki: 9 nM). Flovagatran can be used in the research of arterial and venous thrombosis.
-
In Vitro——
-
In VivoFlovagatran (2.5-mg/kg bolus plus 10 mg/kg/h for 90 minutes) produces anticoagulation effects in dogs.Animal Model:Chicks Dosage:1.0-mg/kg bolus and then 4 mg/kg/h for 90 minutes.2.5-mg/kg bolus and then 10 mg/kg/h for 90 minutes.5.0-mg/kg bolus and then 20 mg/kg/h for 90 minutes.Administration:Bolus plus infusion Result:Elevated PD markers, and produced minimal post-operative blood loss.
-
Synonyms——
-
PathwayAutophagy
-
TargetThrombin
-
RecptorThrombin
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number871576-03-3
-
Formula Weight525.4
-
Molecular FormulaC27H36BN3O7
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC([C@@H](CC1=CC=CC=C1)NC(OCC2=CC=CC=C2)=O)(=O)N3[C@H](C(N[C@@H](CCCOC)B(O)O)=O)CCC3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Nelson DA, et al. Pharmacodynamic and efficacy profile of TGN 255, a novel direct thrombin inhibitor, in canine cardiopulmonary bypass and simulated mitral valve repair. J Extra Corpor Technol. 2008 Jun;40(2):116-22. ?
molnova catalog



related products
-
Pirodomast
Pirodomast is a thromboxane A (TXA2) synthase inhibitor.
-
NP-313
NP-313 (NSC-4264) is a potent antithrombotic agent that inhibits platelet aggregation and activation by inhibiting thromboxane A 2 synthesis and selectively inhibiting SOCC-mediated Ca2+ efflux.
-
Ximelagatran
Ximelagatran, a direct thrombin inhibitor, can be taken orally and acts solely by inhibiting the actions of thrombin. Ximelagatran is converted to the active agent melagatran in vivo.