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Flanvotumab
CAS No. 1188277-05-5
Flanvotumab( —— )
Catalog No. M36794 CAS No. 1188277-05-5
Flanvotumab (IMC-20D7S) is a humanized monoclonal antibody targeting tyrosinase-related protein (TYRP1), exhibiting potent antitumor activity through natural killer-mediated and antibody-dependent cell-mediated cytotoxicity (ADCC).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 342 | Get Quote |
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| 5MG | 618 | Get Quote |
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| 10MG | 941 | Get Quote |
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| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameFlanvotumab
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NoteResearch use only, not for human use.
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Brief DescriptionFlanvotumab (IMC-20D7S) is a humanized monoclonal antibody targeting tyrosinase-related protein (TYRP1), exhibiting potent antitumor activity through natural killer-mediated and antibody-dependent cell-mediated cytotoxicity (ADCC).
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DescriptionFlanvotumab (IMC-20D7S) is a human monoclonal antibody targeting to tyrosinase-related protein (TYRP1), specifically expressed in melanocytes and melanoma cells. Flanvotumab acts function via natural killing-mediated antibody-dependent cell-mediated cytotoxicity (ADCC). Flanvotumab has potent anti-tumor activity and good tolerance.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayProteasome/Ubiquitin
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TargetTyrosinase
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RecptorTyrosinase
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Research Area——
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Indication——
Chemical Information
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CAS Number1188277-05-5
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Formula Weight
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Molecular Formula——
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Khalil DN, et al. An Open-Label, Dose-Escalation Phase I Study of Anti-TYRP1 Monoclonal Antibody IMC-20D7S for Patients with Relapsed or Refractory Melanoma. Clin Cancer Res. 2016 Nov 1;22(21):5204-5210.?
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