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Home - Products - Proteasome/Ubiquitin - Tyrosinase - EGFR-IN-87

EGFR-IN-87

CAS No. 1835666-87-9

EGFR-IN-87( —— )

Catalog No. M37255 CAS No. 1835666-87-9

EGFR-IN-87 is a potent EGFR tyrosine kinase inhibitor with anticancer activity that inhibits EGFR_d746-750, EGFR_L858R/T790M, and EGFR_WT in A431 cells, and can be used for cancer research.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 296 Get Quote
5MG 459 Get Quote
10MG 657 Get Quote
25MG 994 Get Quote
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Biological Information

  • Product Name
    EGFR-IN-87
  • Note
    Research use only, not for human use.
  • Brief Description
    EGFR-IN-87 is a potent EGFR tyrosine kinase inhibitor with anticancer activity that inhibits EGFR_d746-750, EGFR_L858R/T790M, and EGFR_WT in A431 cells, and can be used for cancer research.
  • Description
    EGFR-IN-87 is a EGFR tyrosine kinase inhibitor. EGFR-IN-87 has IC50 value of 3.1 nM, 1.3 nM and 7.1 nM for EGFR_d746-750, EGFR_L858R/T790 and EGFR_WT in A431 cells, respectively. EGFR-IN-87 can be used for cancer diseases research.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Tyrosinase
  • Recptor
    Tyrosine Kinases
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1835666-87-9
  • Formula Weight
    499.61
  • Molecular Formula
    C28H33N7O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(C=C)NC1=CC(NC2=NC=CC(=N2)N3C=C(C=4C=CC=CC43)C)=C(OC)C=C1N(C)CCN(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Song Y.T, et al. Selective inhibitors of clinically important mutants of the egfr tyrosine kinase. The United States, WO2017120429 A1. 2017-07-13.
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