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EGFR-IN-87

CAS No. 1835666-87-9

EGFR-IN-87( —— )

Catalog No. M37255 CAS No. 1835666-87-9

EGFR-IN-87 is a potent EGFR tyrosine kinase inhibitor with anticancer activity that inhibits EGFR_d746-750, EGFR_L858R/T790M, and EGFR_WT in A431 cells, and can be used for cancer research.

Purity : >98% (HPLC)

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Datasheet

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HPLC

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Size	Price / USD	Stock	Quantity
2MG	296	Get Quote
5MG	459	Get Quote
10MG	657	Get Quote
25MG	994	Get Quote
50MG	1371	Get Quote
100MG	1773	Get Quote
500MG	Get Quote	Get Quote
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Biological Information

Product Name

EGFR-IN-87
Note

Research use only, not for human use.
Brief Description

EGFR-IN-87 is a potent EGFR tyrosine kinase inhibitor with anticancer activity that inhibits EGFR_d746-750, EGFR_L858R/T790M, and EGFR_WT in A431 cells, and can be used for cancer research.
Description

EGFR-IN-87 is a EGFR tyrosine kinase inhibitor. EGFR-IN-87 has IC50 value of 3.1 nM, 1.3 nM and 7.1 nM for EGFR_d746-750, EGFR_L858R/T790 and EGFR_WT in A431 cells, respectively. EGFR-IN-87 can be used for cancer diseases research.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Proteasome/Ubiquitin
Target

Tyrosinase
Recptor

Tyrosine Kinases
Research Area

——
Indication

——

Chemical Information

CAS Number

1835666-87-9
Formula Weight

499.61
Molecular Formula

C28H33N7O2
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(C=C)NC1=CC(NC2=NC=CC(=N2)N3C=C(C=4C=CC=CC43)C)=C(OC)C=C1N(C)CCN(C)C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Song Y.T, et al. Selective inhibitors of clinically important mutants of the egfr tyrosine kinase. The United States, WO2017120429 A1. 2017-07-13.

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