Fipronil( Fipronil | HSDB 7051 | MB 46030 | M&B 46030 )

Catalog No. M10721 CAS No. 120068-37-3

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Product Name

Fipronil
Note

Research use only, not for human use.
Brief Description

Fipronil is a broad-use insecticide that belongs to the phenylpyrazole chemical family.
Description

Fipronil is a broad-use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is a broad-spectrum insecticide that disrupts the insect central nervous system by blocking GABA-gated chloride channels and glutamate-gated chloride (GluCl) channels, resulting in central nervous system toxicity. This causes hyperexcitation of contaminated insects' nerves and muscles. Specificity of fipronil on insects may come from a better efficacy on GABA receptor, but also because GluCl channels do not exist in mammals.
In Vitro

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In Vivo

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Synonyms

Fipronil | HSDB 7051 | MB 46030 | M&B 46030
Pathway

Membrane Transporter/Ion Channel
Target

GAT
Recptor

GABA| GluCl channels
Research Area

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Indication

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CAS Number

120068-37-3
Formula Weight

437.15
Molecular Formula

C12H4Cl2F6N4OS
Purity

>98% (HPLC)
Solubility

DMSO: 10 mM
SMILES

N#CC1=NN(C2=C(Cl)C=C(C(F)(F)F)C=C2Cl)C(N)=C1S(C(F)(F)F)=O
Chemical Name

5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl)pyrazole-3-carbonitrile

1.Zaluski R, et al. Environ Toxicol Chem. 2015 May;34(5):1062-9.

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