Fantofarone ( SR 33557; SR-33557;Fantofarone )

Catalog No. M17837 CAS No. 114432-13-2

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HNMR

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Product Name

Fantofarone
Note

Research use only, not for human use.
Brief Description

Fantofarone is a highly potent Calcium Channel antagonist.
Description

Fantofarone, also known as SR 33557, is a highly potent calcium channel antagonist representative of a new class of slow channel blockers. Fantofarone can significantly modify cardiac function and in particular, decrease MO2C consumption during periods of elevated heart rate. Fantofarone is able to induce submaximal peripheral vasodilating effects at doses that are devoid of any clinically significant cardiac effect.
Synonyms

SR 33557; SR-33557;Fantofarone
Pathway

Others
Target

Other Targets
Recptor

Calcium Channel
Research Area

——
Indication

——

CAS Number

114432-13-2
Formula Weight

550.72
Molecular Formula

C31H38N2O5S
Purity

96%
Solubility

DMSO : 150 mg/mL 272.38 mM;
SMILES

COc1ccc(cc1OC)CCN(C)CCCOc2ccc(cc2)S(=O)(=O)c3c4ccccn4cc3C(C)C
Chemical Name

N-(3,4-dimethoxyphenethyl)-3-(4-((2-isopropylindolizin-1-yl)sulfonyl)phenoxy)-N-methylpropan-1-amine

1.Adovelande J, et al. Biochem Pharmacol. 1998 Feb 15;55(4):433-40.

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