FTIDC ( FTIDC )

Catalog No. M17636 CAS No. 873551-53-2

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

FTIDC
Note

Research use only, not for human use.
Brief Description

FTIDC is a highly potent and selective allosteric antagonist of mGluR1 receptors and shows very weak potency against human and rat mGluR5 receptors.
Description

FTIDC is a highly potent and selective allosteric antagonist of mGluR1 receptors and shows very weak potency against human and rat mGluR5 receptors. The inhibition of FTIDC for mGluR1 receptors is shown to be in noncompetitive manner and displays IC50 values of 5.8 and 3.1 nM for human and mouse mGluR1 expressed in CHO cells respectively.
Synonyms

FTIDC
Pathway

Others
Target

Other Targets
Recptor

mGluR1
Research Area

——
Indication

——

CAS Number

873551-53-2
Formula Weight

358.42
Molecular Formula

C18H23FN6O
Purity

95%
Solubility

——
SMILES

C1CC(=CCN1C(=O)N(C(C)C)C)c1nnn(c1C)c1c(nccc1)F
Chemical Name

4-[1-(2-Fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide

1. Ito S, et al. Bioorg Med Chem. 2008 Nov 15;16(22):9817-29.

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