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FOXO1-IN-8

CAS No. ——

FOXO1-IN-8( FOXO1 inhibitor 8 )

Catalog No. M16924 CAS No. ——

A small molecule, selective FOXO1 inhibitor that inhibits FOXO-dependent glucose production devoid of lipogenic activity in hepatocytes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    FOXO1-IN-8
  • Note
    Research use only, not for human use.
  • Brief Description
    A small molecule, selective FOXO1 inhibitor that inhibits FOXO-dependent glucose production devoid of lipogenic activity in hepatocytes.
  • Description
    A small molecule, selective FOXO1 inhibitor that inhibits FOXO-dependent glucose production devoid of lipogenic activity in hepatocytes; shows beneficial effects of FOXO1 inhibition on diabetic hyperglycemia by reducing hepatic glucose production.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    FOXO1 inhibitor 8
  • Pathway
    Nuclear Receptor/Transcription Factor
  • Target
    Foxo1
  • Recptor
    Foxo1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    ——
  • Formula Weight
    243.27
  • Molecular Formula
    C12H13N5O
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    ——
  • Chemical Name
    2-(2-(methylamino)pyrimidin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Langlet F, et al. Cell. 2017 Nov 2;171(4):824-835.e18.
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