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FEN1-IN-2

CAS No. 824983-94-0

FEN1-IN-2( —— )

Catalog No. M35240 CAS No. 824983-94-0

FEN1-IN-2 is a selective and potent inhibitor of flap endonuclease 1 (FEN1), inhibits FEN1 and XPG, has potential anticancer activity, and can be used to study DNA damage repair.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 148 Get Quote
10MG 235 Get Quote
25MG 456 Get Quote
50MG 724 Get Quote
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Biological Information

  • Product Name
    FEN1-IN-2
  • Note
    Research use only, not for human use.
  • Brief Description
    FEN1-IN-2 is a selective and potent inhibitor of flap endonuclease 1 (FEN1), inhibits FEN1 and XPG, has potential anticancer activity, and can be used to study DNA damage repair.
  • Description
    FEN1-IN-2 (compound 20) is a flap endonuclease 1 (FEN1) inhibitor, with IC50 values of 3 nM and 226 nM for FEN1 and XPG, respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    824983-94-0
  • Formula Weight
    393.42
  • Molecular Formula
    C20H15N3O4S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (254.18 mM; Ultrasonic )
  • SMILES
    O=C(N)C1=CC=C(C=C1)C=2C=CC=C(C2)CN3C(=O)N(O)C(=O)C=4SC=CC43
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. L Nathan Tumey, et al. The identification and optimization of a N-hydroxy urea series of flap endonuclease 1 inhibitors. Bioorg Med Chem Lett. 2005 Jan 17;15(2):277-81.?
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