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NXY-059

CAS No. 168021-79-2

NXY-059( NXY 059 | NXY059 | Disufenton sodium )

Catalog No. M12566 CAS No. 168021-79-2

NXY-059 (Disufenton sodium) is a free radical-trapping agent that demonstrates a considerable neuroprotective effect in vivo.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 38 In Stock
5MG 35 In Stock
10MG 57 In Stock
25MG 112 In Stock
50MG 181 In Stock
100MG 276 In Stock
200MG 426 In Stock
500MG 691 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    NXY-059
  • Note
    Research use only, not for human use.
  • Brief Description
    NXY-059 (Disufenton sodium) is a free radical-trapping agent that demonstrates a considerable neuroprotective effect in vivo.
  • Description
    NXY-059 (Disufenton sodium) is a free radical-trapping agent that demonstrates a considerable neuroprotective effect in vivo; exhibits a substantial protective effect, lessening the disability caused by an experimentally induced stroke in a primate species, shows significantly decreased neurological impairment in rat model of hemorrhagic stroke.Stroke Phase 3 Discontinued.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NXY 059 | NXY059 | Disufenton sodium
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Neurological Disease
  • Indication
    Stroke

Chemical Information

  • CAS Number
    168021-79-2
  • Formula Weight
    381.3329
  • Molecular Formula
    C11H13NNa2O7S2
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    CC(C)(C)[N+](=CC1=C(C=C(C=C1)S(=O)(=O)[O-])S(=O)(=O)[O-])[O-].[Na+].[Na+]
  • Chemical Name
    1,3-Benzenedisulfonic acid, 4-[[(1,1-dimethylethyl)oxidoimino]methyl]-, sodium salt (1:2)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Marshall JW, et al. Stroke. 2001 Jan;32(1):190-8. 2. Kuroda S, et al. J Cereb Blood Flow Metab. 1999 Jul;19(7):778-87. 3. Peeling J, et al. Neuropharmacology. 2001 Mar;40(3):433-9. 4. Sydserff SG, et al. Br J Pharmacol. 2002 Jan;135(1):103-12.
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