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FEN1-IN-1

CAS No. 824983-91-7

FEN1-IN-1 ( LNT-1 )

Catalog No. M24814 CAS No. 824983-91-7

FEN1-IN-1 is an inhibitor of flap endonuclease 1 (FEN1). FEN1-IN-1 binds to the active site of FEN1. It partly achieves inhibition by the co-ordination of Mg2+ ions.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 45 In Stock
10MG 67 In Stock
25MG 103 In Stock
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Biological Information

  • Product Name
    FEN1-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    FEN1-IN-1 is an inhibitor of flap endonuclease 1 (FEN1). FEN1-IN-1 binds to the active site of FEN1. It partly achieves inhibition by the co-ordination of Mg2+ ions.
  • Description
    FEN1-IN-1 is an inhibitor of flap endonuclease 1 (FEN1). FEN1-IN-1 binds to the active site of FEN1. It partly achieves inhibition by the co-ordination of Mg2+ ions.
  • Synonyms
    LNT-1
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    flap endonuclease 1 (FEN1)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    824983-91-7
  • Formula Weight
    332.3
  • Molecular Formula
    C15H12N2O5S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:250 mg/mL (752.26 mM; Need ultrasonic)
  • SMILES
    ON(C(c(scc1)c1N1CC2Oc(cccc3)c3OC2)=O)C1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ward TA, et al. Small molecule inhibitors uncover synthetic genetic interactions of human flap endonuclease 1 (FEN1) with DNA damage response genes. PLoS One. 2017 Jun 19;12(6):e0179278.
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