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FC-116

CAS No. 2417298-29-2

FC-116( —— )

Catalog No. M36931 CAS No. 2417298-29-2

FC-116 is a potent Tubulin inhibitor with antitumour activity and inhibits tumour growth in mice.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 128 In Stock
5MG 188 In Stock
10MG 312 In Stock
25MG 533 In Stock
50MG 760 In Stock
100MG 981 In Stock
500MG 2007 In Stock
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Biological Information

  • Product Name
    FC-116
  • Note
    Research use only, not for human use.
  • Brief Description
    FC-116 is a potent Tubulin inhibitor with antitumour activity and inhibits tumour growth in mice.
  • Description
    FC-11 is a Tubulin inhibitor that effectively inhibits tumor growth in mice. FC-11 can also induce endoplasmic reticulum (ER) stress to generate excess reactive oxygen species (ROS), leading to mitochondrial damage, thereby promoting apoptosis in colorectal cancer (CRC) cells by targeting microtubules. FC-11 can be used in cancer research.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis | Microtubule Associated
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2417298-29-2
  • Formula Weight
    369.39
  • Molecular Formula
    C21H20FNO4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(=C(/C(=O)C1=CC(OC)=C(OC)C(OC)=C1)\C)\C=2C=3C(NC2)=CC(F)=CC3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Liu X, et al. Fluoroindole chalcone analogues targeting the colchicine binding site of tubulin for colorectal oncotherapy. Eur J Med Chem. 2023 Sep 5;257:115540.?
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