FC-116( —— )

Catalog No. M36931 CAS No. 2417298-29-2

FC-116 is a potent Tubulin inhibitor with antitumour activity and inhibits tumour growth in mice.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	128	In Stock
5MG	188	In Stock
10MG	312	In Stock
25MG	533	In Stock
50MG	760	In Stock
100MG	981	In Stock
500MG	2007	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

FC-116
Note

Research use only, not for human use.
Brief Description

FC-116 is a potent Tubulin inhibitor with antitumour activity and inhibits tumour growth in mice.
Description

FC-11 is a Tubulin inhibitor that effectively inhibits tumor growth in mice. FC-11 can also induce endoplasmic reticulum (ER) stress to generate excess reactive oxygen species (ROS), leading to mitochondrial damage, thereby promoting apoptosis in colorectal cancer (CRC) cells by targeting microtubules. FC-11 can be used in cancer research.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Apoptosis
Target

Apoptosis
Recptor

Apoptosis | Microtubule Associated
Research Area

——
Indication

——

Chemical Information

CAS Number

2417298-29-2
Formula Weight

369.39
Molecular Formula

C21H20FNO4
Purity

>98% (HPLC)
Solubility

——
SMILES

C(=C(/C(=O)C1=CC(OC)=C(OC)C(OC)=C1)\C)\C=2C=3C(NC2)=CC(F)=CC3
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Liu X, et al. Fluoroindole chalcone analogues targeting the colchicine binding site of tubulin for colorectal oncotherapy. Eur J Med Chem. 2023 Sep 5;257:115540.?

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