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Eupatolide
CAS No. 6750-25-0
Eupatolide( —— )
Catalog No. M29300 CAS No. 6750-25-0
Eupatolide is isolated from the flowers of Inula japonica with anti-inflammatory activity. Eupatolide can be used in studies about TRAIL resistance in breast cancer cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 100MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameEupatolide
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NoteResearch use only, not for human use.
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Brief DescriptionEupatolide is isolated from the flowers of Inula japonica with anti-inflammatory activity. Eupatolide can be used in studies about TRAIL resistance in breast cancer cells.
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DescriptionEupatolide is isolated from the flowers of Inula japonica with anti-inflammatory activity. Eupatolide can be used in studies about TRAIL resistance in breast cancer cells.(In Vitro):Eupatolide exhibits potent cytotoxicity against HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cancer cell lines (IC50: 1.57 to 22.58 uM). Eupatolide sensitizes breast cancer cells to TRAIL through the down-regulation of c-FLIP expression. In RAW264.7 cells, Eupatolide inhibits lipopolysaccharide-induced COX-2 and iNOS expression by inducing proteasomal degradation of TRAF6. Eupatolide suppresses PDGF-induced proliferation and migration of VSMC through HO-1 induction via ROS-Nrf2 pathway and may be a potential HO-1 inducer for preventing or treating vascular diseases.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetTNF
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RecptorTNF
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Research Area——
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Indication——
Chemical Information
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CAS Number6750-25-0
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Formula Weight248.32
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Molecular FormulaC15H20O3
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Purity>98% (HPLC)
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Solubility——
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SMILESC=C1[C@]2([C@](OC1=O)(/C=C(\C)/CC/C=C(\C)/C[C@H]2O)[H])[H]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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