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Etravirine

CAS No. 269055-15-4

Etravirine ( R-165335;TMC-125 )

Catalog No. M13823 CAS No. 269055-15-4

A second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) for treatment of HIV-1 infection.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 61 In Stock
10MG 102 In Stock
25MG 178 In Stock
50MG 264 In Stock
100MG 363 In Stock
200MG 460 In Stock
500MG 746 In Stock
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Biological Information

  • Product Name
    Etravirine
  • Note
    Research use only, not for human use.
  • Brief Description
    A second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) for treatment of HIV-1 infection.
  • Description
    A second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) for treatment of HIV-1 infection.HIV Infection Approved
  • Synonyms
    R-165335;TMC-125
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    ReverseTranscriptase
  • Research Area
    Infection
  • Indication
    HIV Infection

Chemical Information

  • CAS Number
    269055-15-4
  • Formula Weight
    435.28
  • Molecular Formula
    C20H15BrN6O
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    N#CC1=CC(C)=C(OC2=NC(NC3=CC=C(C#N)C=C3)=NC(N)=C2Br)C(C)=C1
  • Chemical Name
    Benzonitrile, 4-[[6-amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Das K, et al. J Med Chem, 2004, 47(10), 2550-2560.
2. Andries K, et al. Antimicrob Agents Chemother. 2004 Dec;48(12):4680-6.
3. Sankatsing SU, et al. AIDS. 2003 Dec 5;17(18):2623-7.
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