Etimizol

CAS No. 64-99-3

Etimizol ( Ethimizole; Ethymisol; Ethymisole )

Catalog No. M26209 CAS No. 64-99-3

Etimizol?was shown to relieve amnesia effectively in the origin of which there is the hypoxic component (hypobaric hypoxia, actinomycin D, mechanical injury of the brain).?

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 177 Get Quote
25MG 327 Get Quote
50MG 507 Get Quote
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Biological Information

  • Product Name
    Etimizol
  • Note
    Research use only, not for human use.
  • Brief Description
    Etimizol?was shown to relieve amnesia effectively in the origin of which there is the hypoxic component (hypobaric hypoxia, actinomycin D, mechanical injury of the brain).?
  • Description
    Etimizol?was shown to relieve amnesia effectively in the origin of which there is the hypoxic component (hypobaric hypoxia, actinomycin D, mechanical injury of the brain).?(In Vivo):Extracellular application of 5--10 mM/L Etimizol (Ethymisole) exerted a specific effect on the giant neurons of the Coretus corneus isolated nervous system: action potential duration increased significantly, speed of development of its descending phase decreased, as well as the trace hyperpolarization amplitude .The time interval between administration ofetimizol (3 mg/kg) and the onset of learning varied between 0.5 and 3 h in the several series.?Etimizol (Ethymisole) did not facilitate the learning in rats whatever the time of administration and biological modality of reinforcement .?After administration of Etimizol (Ethymisole) at doses of 10 or 1 mg/loop mean residence time of etimizol in the loop was 20.1 and 7.6 min, respectively, with mean standard deviation being 3.1 and 0.8, respectively .
  • Synonyms
    Ethimizole; Ethymisol; Ethymisole
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    H1 receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    64-99-3
  • Formula Weight
    210.2
  • Molecular Formula
    C9H14N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CCn1cnc(C(=O)NC)c1C(=O)NC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Abdi A, Rose E, Levine M. Diphenhydramine overdose with intraventricular conduction delay treated with hypertonic sodium bicarbonate and i.v. lipid emulsion. West J Emerg Med. 2014 Nov;15(7):855-8.
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