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Etelcalcetide

CAS No. 1262780-97-1

Etelcalcetide( AMG 416; KAI-4169 )

Catalog No. M29934 CAS No. 1262780-97-1

Etelcalcetide (AMG 416) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Etelcalcetide
  • Note
    Research use only, not for human use.
  • Brief Description
    Etelcalcetide (AMG 416) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis.
  • Description
    Etelcalcetide (AMG 416) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    AMG 416; KAI-4169
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1262780-97-1
  • Formula Weight
    1048.25
  • Molecular Formula
    C38H73N21O10S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    Sequence:{Cys1'}-Ac-{d-Cys1}-{d-Ala}-{d-Arg}-{d-Arg}-{d-Arg}-{d-Ala}-{d-Arg}-NH2 (Disulfide bridge: Cys1'-Cys1)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Block GA, et al. Effect of Etelcalcetide vs Cinacalcet on Serum Parathyroid Hormone in Patients Receiving Hemodialysis With Secondary Hyperparathyroidism: A Randomized Clinical Trial. JAMA. 2017 Jan 10;317(2):156-164.
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