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Biotin-EDA

CAS No. 111790-37-5

Biotin-EDA( —— )

Catalog No. M26901 CAS No. 111790-37-5

Biotin-EDA is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Biotin-EDA
Note

Research use only, not for human use.
Brief Description

Biotin-EDA is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
Description

Biotin-EDA is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

STING
Research Area

——
Indication

——

Chemical Information

CAS Number

111790-37-5
Formula Weight

286.39
Molecular Formula

C12H22N4O2S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (174.59 mM)
SMILES

[H][C@]12CS[C@@H](CCCCC(=O)NCCN)[C@@]1([H])NC(=O)N2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Hong Z, et, al. STING inhibitors target the cyclic dinucleotide binding pocket. Proc Natl Acad Sci U S A. 2021 Jun 15;118(24):e2105465118.

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