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Biotin-EDA

CAS No. 111790-37-5

Biotin-EDA( —— )

Catalog No. M26901 CAS No. 111790-37-5

Biotin-EDA is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Biotin-EDA
  • Note
    Research use only, not for human use.
  • Brief Description
    Biotin-EDA is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
  • Description
    Biotin-EDA is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    STING
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    111790-37-5
  • Formula Weight
    286.39
  • Molecular Formula
    C12H22N4O2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (174.59 mM)
  • SMILES
    [H][C@]12CS[C@@H](CCCCC(=O)NCCN)[C@@]1([H])NC(=O)N2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hong Z, et, al. STING inhibitors target the cyclic dinucleotide binding pocket. Proc Natl Acad Sci U S A. 2021 Jun 15;118(24):e2105465118.
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