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Home - Products - Cytoskeleton/Cell Adhesion Molecules - Microtubule/Tubulin - Estramustine

Estramustine

CAS No. 2998-57-4

Estramustine( NSC89201 | LEO275 )

Catalog No. M27308 CAS No. 2998-57-4

Estramustine is a nitrogen mustard linked to estradiol, usually as phosphate. Estramustine has been used to treat prostatic neoplasms; also has radiation protective properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 212 Get Quote
5MG 302 Get Quote
10MG 494 Get Quote
25MG 797 Get Quote
50MG 1071 Get Quote
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Biological Information

  • Product Name
    Estramustine
  • Note
    Research use only, not for human use.
  • Brief Description
    Estramustine is a nitrogen mustard linked to estradiol, usually as phosphate. Estramustine has been used to treat prostatic neoplasms; also has radiation protective properties.
  • Description
    Estramustine is a nitrogen mustard linked to estradiol, usually as phosphate. Estramustine has been used to treat prostatic neoplasms; also has radiation protective properties. Estramustine is selectively taken up by prostate cells and exerts antineoplastic effects by interfering with microtubule of dynamics and by reducing plasma levels of testosterone.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NSC89201 | LEO275
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Microtubule/Tubulin
  • Recptor
    Ephrin Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2998-57-4
  • Formula Weight
    440.4
  • Molecular Formula
    C23H31Cl2NO3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (227.07 mM)
  • SMILES
    C[C@@]12[C@@H](O)CC[C@@]1([H])[C@]3([H])CCC4=C(C=CC(OC(N(CCCl)CCCl)=O)=C4)[C@@]3([H])CC2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wu B, et al. Potent and Selective EphA4 Agonists for the Treatment of ALS. Cell Chem Biol. 2017 Mar 16;24(3):293-305.
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