
Espindolol
CAS No. 26328-11-0
Espindolol( AGI-001 | MT-102 | AGI001 | MT102 | AGI 001 | MT 102 )
Catalog No. M27876 CAS No. 26328-11-0
Espindolol is a novel non-selective β blocker with central 5-HT1a and partial β2 receptor agonist effects.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 210 | Get Quote |
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10MG | 302 | Get Quote |
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25MG | 608 | Get Quote |
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50MG | 913 | Get Quote |
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100MG | Get Quote | Get Quote |
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200MG | Get Quote | Get Quote |
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500MG | Get Quote | Get Quote |
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1G | Get Quote | Get Quote |
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Biological Information
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Product NameEspindolol
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NoteResearch use only, not for human use.
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Brief DescriptionEspindolol is a novel non-selective β blocker with central 5-HT1a and partial β2 receptor agonist effects.
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DescriptionEspindolol is a novel non-selective β blocker with central 5-HT1a and partial β2 receptor agonist effects.(In Vivo):Placebo-treated rats progressively lost body weight (-15.5 ± 7.2 g), lean mass (-1.5 ± 4.2 g), and fat mass (-15.6 ± 2.7 g), while espindolol treatment increased body weight (+8.0 ± 6.1 g, p < 0.05), particularly lean mass (+43.4 ± 3.5 g, p < 0.001), and reduced fat mass further (-38.6 ± 3.4 g, p < 0.001). Anabolic/catabolic signaling was assessed in gastrocnemius muscle. Espindolol decreased proteasome and caspase-3 proteolytic activities by approximately 50 % (all p < 0.05).
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In Vitro——
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In VivoAnimal Model:Male Sprague Dawley ratsDosage:15 mg/kg Administration:Intraperitoneal injection; 15 mg/kg, 20 min acute treatment or 24 h, 16 h and 20 min short-term treatment before [3H]-WAY 100635 injection Result:Reduced [3H]-WAY 100635 accumulation in 5-HT1A receptor-containing brain areas, but showed no effect on the dorsal raphe nucleus (DRN), and the CA1 and CA3 hippocampal areas.
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SynonymsAGI-001 | MT-102 | AGI001 | MT102 | AGI 001 | MT 102
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number26328-11-0
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Formula Weight248.326
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Molecular FormulaC14H20N2O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (402.71 mM)
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SMILESCC(C)NC[C@H](O)COc1cccc2[nH]ccc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference



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