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Esculetin

CAS No. 305-01-1

Esculetin ( Asculetine; CCRIS 7065; CCRIS-7065; CCRIS7065 )

Catalog No. M18396 CAS No. 305-01-1

Esculetin is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Esculetin can be found in a number of food items such as dandelion, highbush blueberry, wild leek, and opium poppy.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Esculetin
  • Note
    Research use only, not for human use.
  • Brief Description
    Esculetin is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Esculetin can be found in a number of food items such as dandelion, highbush blueberry, wild leek, and opium poppy.
  • Description
    Esculetin is a β-catenin inhibitor found in chicory and other plant sources. It displays a wide variety of activities, including inhibiting MPTP-induced neurotoxicity and neuronal apoptosis, decreasing body weight, triglyceride levels, total cholesterol and glucose levels in high-fat diet-fed animals, and suppressing proliferation of colon cancer cells.
  • Synonyms
    Asculetine; CCRIS 7065; CCRIS-7065; CCRIS7065
  • Pathway
    GPCR/G Protein
  • Target
    Histamine Receptor
  • Recptor
    Others
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    305-01-1
  • Formula Weight
    178.14
  • Molecular Formula
    C9H6O4
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    c1cc(=O)oc2cc(c(cc12)O)O
  • Chemical Name
    6,7-dihydroxy-2H-chromen-2-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Cho JH, et al. Int J Oncol. 2015 Jan;46(1):265-71.
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